133299

• Gene Symbol: ALS2
• Gene Name: ALS2, alsin Rho guanine nucleotide exchange factor
• Gene Aliases: ALS2CR6, ALSJ, IAHSP, PLSJ
• Chromosome Location: Chr.2: 201700263 - 201781172 on Build GRCh38
• UniGene ID: Hs.471096
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ALS2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_020919.3	NP_065970.2	9, 10	2362
	XM_006712654.2	XP_006712717.1	9, 10	2939
	XM_006712655.3	XP_006712718.1	5, 6	576
	XM_011511530.2	XP_011509832.1	8, 9	2074
	XM_017004569.1	XP_016860058.1	8, 9	2066
	XM_017004570.1	XP_016860059.1	8, 9	2066
	XM_017004571.1	XP_016860060.1	8, 9	2004
	XM_017004572.1	XP_016860061.1	6, 7	1551
GenBank mRNA	AB046783.2	-	8, 9	2083
	AB053305.1	-	9, 10	2129
	AF391100.1	-	9, 10	2129
	AK291029.1	-	9, 10	2146
	BC029174.1	-	9, 10	2132
	BC071576.1	-	9, 10	2124	30347073
	KU178735.1	-	8, 9	2006
	KU178736.1	-	8, 9	1944

More Information

Gene Ontology Categories:

Process(es)

behavioral fear response
in utero embryonic development
receptor recycling
response to oxidative stress
endosome organization
axonogenesis
neuromuscular junction development
locomotory behavior
protein localization
cell death
vesicle organization
endosomal transport
Rac protein signal transduction
positive regulation of Rac protein signal transduction
regulation of Rho protein signal transduction
synaptic transmission, glutamatergic
positive regulation of GTPase activity
positive regulation of protein kinase activity
neuron projection morphogenesis
regulation of endosome size
positive regulation of protein serine/threonine kinase activity

Function(s)

guanyl-nucleotide exchange factor activity
Ran guanyl-nucleotide exchange factor activity
protein binding
Rab guanyl-nucleotide exchange factor activity
Rab GTPase binding
Rac guanyl-nucleotide exchange factor activity
protein homodimerization activity
protein serine/threonine kinase activator activity