135366

Gene Symbol:

RTEL1-TNFRSF6B RTEL1

Gene Name:

RTEL1-TNFRSF6B readthrough (NMD candidate)

regulator of telomere elongation helicase 1

Gene Aliases:

-

C20orf41, DKCA4, DKCB5, NHL, PFBMFT3, RTEL

Chromosome Location:

Chr.20: 63657810 - 63698698 on Build GRCh38

Chromosome Location:

Chr.20: 63657810 - 63696253 on Build GRCh38

UniGene ID:

Hs.745057

Hs.745057

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: RTEL1-TNFRSF6B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_037882.1		2	912

Gene Symbol: RTEL1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001283009.1	NP_001269938.1	2	912
	NM_016434.3	NP_057518.1	2	912
	NM_032957.4	NP_116575.3	2	912
GenBank mRNA	AF217795.1	-	2	912
	AK299332.1	-	2	407
	AK302508.1	-	2	431
	JX119186.1	-	1	85

More Information

Panther Classification:

Molecular Function -

DNA helicase

Gene Ontology Categories:

Process(es)

telomere maintenance
strand displacement
DNA repair
regulation of double-strand break repair via homologous recombination
replication fork processing
positive regulation of telomere maintenance
DNA duplex unwinding
telomere maintenance in response to DNA damage
telomeric loop disassembly
mitotic telomere maintenance via semi-conservative replication
positive regulation of telomere capping
positive regulation of telomere maintenance via telomere lengthening
negative regulation of t-circle formation
negative regulation of telomere maintenance in response to DNA damage
positive regulation of telomeric loop disassembly

Function(s)

DNA binding
ATP-dependent DNA helicase activity
protein binding
ATP binding
metal ion binding
4 iron, 4 sulfur cluster binding