136463

• Gene Symbol: SIRT4
• Gene Name: sirtuin 4
• Gene Aliases: SIR2L4
• Chromosome Location: Chr.12: 120292199 - 120313242 on Build GRCh38
• UniGene ID: Hs.50861
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SIRT4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012240.2	NP_036372.1	3	811
	XM_005253865.4	XP_005253922.1	3	539
	XM_006719308.2	XP_006719371.1	3	1497
	XM_006719309.3	XP_006719372.1	3	993
GenBank mRNA	AF083109.1	-	3	772
	BC109319.3	-	3	772	40036789
	BC109320.3	-	3	772	40036792

More Information

Gene Ontology Categories:

Process(es)

regulation of glutamine family amino acid metabolic process
chromatin silencing
protein ADP-ribosylation
glutamine metabolic process
cellular response to DNA damage stimulus
negative regulation of cardiac muscle cell apoptotic process
peptidyl-lysine deacetylation
negative regulation of fatty acid oxidation
negative regulation of insulin secretion
positive regulation of lipid biosynthetic process
cellular response to hypoxia
tricarboxylic acid metabolic process
negative regulation of protein processing involved in protein targeting to mitochondrion
regulation of pyruvate dehydrogenase activity

Function(s)

NAD+ ADP-ribosyltransferase activity
protein binding
zinc ion binding
NAD-dependent protein deacetylase activity
biotinidase activity
lipoamidase activity
NAD+ binding