136755

• Gene Symbol: PHF8
• Gene Name: PHD finger protein 8
• Gene Aliases: JHDM1F, MRXSSD, ZNF422
• Chromosome Location: Chr.X: 53936680 - 54048935 on Build GRCh38
• UniGene ID: Hs.133352
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PHF8
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001184896.1	NP_001171825.1	12	1639
	NM_001184897.1	NP_001171826.1	12	1790
	NM_001184898.1	NP_001171827.1	12	1461
	NM_015107.2	NP_055922.1	12	1790
	XM_005261996.1	XP_005262053.1	13	1483
	XM_005261997.3	XP_005262054.1	12	2088
	XM_005261999.1	XP_005262056.1	12	1459
	XM_005262000.1	XP_005262057.1	12	1752
	XM_011530778.1	XP_011529080.1	12	1752
	XM_017029361.1	XP_016884850.1	12	2038
	XM_017029362.1	XP_016884851.1	12	2038
GenBank mRNA	AB029034.1	-	12	1466
	AF091081.1	-	6	583
	AK021696.1	-	11	1294
	AK304272.1	-	12	1612
	BC053861.1	-	12	1494	5138930
	CR933612.1	-	12	1625

More Information

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
transcription, DNA-templated
brain development
histone H3-K9 demethylation
histone H4-K20 demethylation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase I promoter
oxidation-reduction process
negative regulation of chromatin silencing at rDNA
histone H3-K36 demethylation
histone H3-K27 demethylation

Function(s)

chromatin binding
iron ion binding
protein binding
zinc ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
histone demethylase activity
histone demethylase activity (H3-K9 specific)
methylated histone binding
histone demethylase activity (H4-K20 specific)
histone demethylase activity (H3-K36 specific)
histone demethylase activity (H3-K27 specific)