137

• Gene Symbol: IRAK1
• Gene Name: interleukin 1 receptor associated kinase 1
• Gene Aliases: IRAK, pelle
• Chromosome Location: Chr.X: 154010506 - 154019906 on Build GRCh38
• UniGene ID: Hs.522819
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: IRAK1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001025242.1	NP_001020413.1	9	1266
	NM_001025243.1	NP_001020414.1	9	1266
	NM_001569.3	NP_001560.2	9	1266
	XM_005274668.3	XP_005274725.1	8	1288
	XM_011531158.2	XP_011529460.1	9	1281
GenBank mRNA	AF346607.1	-	9	1187
	BC014963.1	-	9	1251	4906853
	BC054000.1	-	8	1343	6164719
	DQ054788.1	-	9	1187
	L76191.1	-	9	1266

More Information

Gene Ontology Categories:

Process(es)

activation of MAPK activity
regulation of cytokine-mediated signaling pathway
toll-like receptor signaling pathway
MyD88-dependent toll-like receptor signaling pathway
protein phosphorylation
signal transduction
transmembrane receptor protein serine/threonine kinase signaling pathway
activation of NF-kappaB-inducing kinase activity
JNK cascade
aging
lipopolysaccharide-mediated signaling pathway
negative regulation of NF-kappaB transcription factor activity
positive regulation of type I interferon production
response to lipopolysaccharide
toll-like receptor 2 signaling pathway
toll-like receptor 4 signaling pathway
toll-like receptor 9 signaling pathway
cellular response to heat
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of MAP kinase activity
innate immune response
positive regulation of transcription, DNA-templated
protein autophosphorylation
positive regulation of smooth muscle cell proliferation
positive regulation of NF-kappaB transcription factor activity
protein oligomerization
nucleotide-binding oligomerization domain containing signaling pathway
interleukin-1-mediated signaling pathway
response to interleukin-1
cellular response to hypoxia

Function(s)

protein kinase activity
protein serine/threonine kinase activity
NF-kappaB-inducing kinase activity
protein binding
ATP binding
kinase activity
heat shock protein binding
protein homodimerization activity
protein heterodimerization activity