137010

• Gene Symbol: DICER1
• Gene Name: dicer 1, ribonuclease III
• Gene Aliases: DCR1, Dicer, Dicer1e, HERNA, K12H4.8-LIKE, MNG1, RMSE2
• Chromosome Location: Chr.14: 95086228 - 95158010 on Build GRCh38
• UniGene ID: Hs.738957
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DICER1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001195573.1	NP_001182502.1	7	1218
	NM_001271282.2	NP_001258211.1	8	1406
	NM_001291628.1	NP_001278557.1	8	1294
	NM_030621.4	NP_085124.2	10	1465
	NM_177438.2	NP_803187.1	8	1411
	XM_011536599.1	XP_011534901.1	10	1597
	XM_011536600.2	XP_011534902.1	10	1472
	XM_011536601.2	XP_011534903.1	11	1617
	XM_011536602.2	XP_011534904.1	11	1508
	XM_011536604.2	XP_011534906.1	7	1293
	XM_017021120.1	XP_016876609.1	10	1904
	XM_017021121.1	XP_016876610.1	8	1299
	XM_017021122.1	XP_016876611.1	9	1343
	XM_017021123.1	XP_016876612.1	9	1774
GenBank mRNA	AB023145.2	-	8	1411
	AJ132261.2	-	8	1414
	BC150287.1	-	8	1411	8860125
	HM595745.1	-	7	1182

More Information

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
apoptotic DNA fragmentation
negative regulation of Schwann cell proliferation
positive regulation of Schwann cell differentiation
nerve development
production of siRNA involved in RNA interference
targeting of mRNA for destruction involved in RNA interference
gene silencing by RNA
pre-miRNA processing
positive regulation of myelination
peripheral nervous system myelin formation
conversion of ds siRNA to ss siRNA involved in RNA interference
siRNA loading onto RISC involved in RNA interference
production of miRNAs involved in gene silencing by miRNA
miRNA loading onto RISC involved in gene silencing by miRNA
conversion of ds siRNA to ss siRNA
neuron projection morphogenesis
RNA phosphodiester bond hydrolysis, endonucleolytic

Function(s)

double-stranded RNA binding
helicase activity
endoribonuclease activity
ribonuclease III activity
deoxyribonuclease I activity
protein binding
ATP binding
protein domain specific binding
siRNA binding
metal ion binding
pre-miRNA binding