137235

• Gene Symbol: TNFSF10
• Gene Name: tumor necrosis factor superfamily member 10
• Gene Aliases: APO2L, Apo-2L, CD253, TL2, TNLG6A, TRAIL
• Chromosome Location: Chr.3: 172505508 - 172523507 on Build GRCh38
• UniGene ID: Hs.478275
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TNFSF10
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001190942.1	NP_001177871.1	3	855
	NM_003810.3	NP_003801.1	5	1003
	NR_033994.1		4	960
GenBank mRNA	AK296085.1	-	3	823
	BC032722.1	-	5	955	5504670
	U37518.1	-	5	967
	U57059.1	-	5	970

More Information

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
immune response
signal transduction
cell surface receptor signaling pathway
cell-cell signaling
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of release of cytochrome c from mitochondria
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

receptor binding
cytokine activity
tumor necrosis factor receptor binding
protein binding
metal ion binding