137247

• Gene Symbol: FADD
• Gene Name: Fas associated via death domain
• Gene Aliases: GIG3, MORT1
• Chromosome Location: Chr.11: 70203163 - 70207402 on Build GRCh38
• UniGene ID: Hs.86131
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: FADD
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003824.3	NP_003815.1	2	1761
GenBank mRNA	BC000334.2	-	2	1612	2822581
	BC025733.1	-	2	1588
	U24231.1	-	2	1593
	X84709.1	-	2	1609

More Information

Gene Ontology Categories:

Process(es)

positive regulation of T cell mediated cytotoxicity
positive regulation of adaptive immune response
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
cell surface receptor signaling pathway
extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of interferon-gamma production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
T cell differentiation in thymus
TRIF-dependent toll-like receptor signaling pathway
TRAIL-activated apoptotic signaling pathway
positive regulation of activated T cell proliferation
T cell homeostasis
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
positive regulation of macrophage differentiation
positive regulation of proteolysis
positive regulation of transcription from RNA polymerase II promoter
lymph node development
spleen development
thymus development
protein heterooligomerization
defense response to virus
positive regulation of type I interferon-mediated signaling pathway
negative regulation of necroptotic process
negative regulation of activation-induced cell death of T cells
cellular response to mechanical stimulus
death-inducing signaling complex assembly
motor neuron apoptotic process
apoptotic signaling pathway
extrinsic apoptotic signaling pathway
extrinsic apoptotic signaling pathway in absence of ligand
activation of cysteine-type endopeptidase activity
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
necroptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

protease binding
death receptor binding
tumor necrosis factor receptor binding
protein binding
protein complex binding
tumor necrosis factor receptor superfamily binding
death effector domain binding
identical protein binding
caspase binding