137296

• Gene Symbol: IQGAP1
• Gene Name: IQ motif containing GTPase activating protein 1
• Gene Aliases: HUMORFA01, SAR1, p195
• Chromosome Location: Chr.15: 90388241 - 90502243 on Build GRCh38
• UniGene ID: Hs.430551
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: IQGAP1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003870.3	NP_003861.1	2	223
GenBank mRNA	AK307643.1	-	2	140
	BC005906.1	-	2	188
	BC020549.1	-	2	167
	BC037425.1	-	2	177
	BC064971.1	-	2	173
	BC089385.1	-	2	174
	BC110811.1	-	2	158
	BC139731.1	-	2	168	40073370
	BC151834.1	-	2	246	9007269
	D29640.1	-	2	246

More Information

Panther Classification:

Molecular Function -

G-protein modulator, protein-binding activity modulator, GTPase-activating protein

Gene Ontology Categories:

Process(es)

regulation of cytokine production
signal transduction
epidermal growth factor receptor signaling pathway
fibroblast growth factor receptor signaling pathway
negative regulation of GTPase activity
negative regulation of dephosphorylation
cellular response to platelet-derived growth factor stimulus
positive regulation of GTPase activity
positive regulation of protein kinase activity
platelet-derived growth factor receptor signaling pathway
cellular response to calcium ion
cellular response to epidermal growth factor stimulus
positive regulation of protein serine/threonine kinase activity
glomerular visceral epithelial cell development
cell-cell adhesion
neuron projection extension

Function(s)

GTPase inhibitor activity
GTPase activator activity
calcium ion binding
protein binding
calmodulin binding
phosphatidylinositol-3,4,5-trisphosphate binding
protein kinase binding
protein phosphatase binding
protein domain specific binding
protein complex binding
protein serine/threonine kinase activator activity
S100 protein binding
Rac GTPase binding
cadherin binding involved in cell-cell adhesion