137419

• Gene Symbol: RNF8
• Gene Name: ring finger protein 8
• Gene Aliases: hRNF8
• Chromosome Location: Chr.6: 37353972 - 37394738 on Build GRCh38
• UniGene ID: Hs.485278
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: RNF8
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003958.3	NP_003949.1	8	4254
	NM_183078.2	NP_898901.1	7	4049
	NR_046399.1		8	4360
GenBank mRNA	AB014546.1	-	8	4173

More Information

Panther Classification:

Molecular Function -

ubiquitin-protein ligase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

double-strand break repair
double-strand break repair via nonhomologous end joining
ubiquitin-dependent protein catabolic process
cellular response to DNA damage stimulus
mitotic nuclear division
spermatid development
response to ionizing radiation
histone H2A ubiquitination
histone H2B ubiquitination
negative regulation of transcription elongation from RNA polymerase II promoter
interstrand cross-link repair
histone exchange
isotype switching
positive regulation of DNA repair
cell division
protein autoubiquitination
protein K63-linked ubiquitination
histone H2A K63-linked ubiquitination
protein K48-linked ubiquitination

Function(s)

chromatin binding
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
ubiquitin protein ligase binding
histone binding
protein homodimerization activity