138262

• Gene Symbol: SOCS5
• Gene Name: suppressor of cytokine signaling 5
• Gene Aliases: CIS6, CISH6, Cish5, SOCS-5
• Chromosome Location: Chr.2: 46698960 - 46762788 on Build GRCh38
• UniGene ID: Hs.468426
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SOCS5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_014011.4	NP_054730.1	2	450
	NM_144949.2	NP_659198.1	2	538
GenBank mRNA	AB014571.1	-	2	458
	AF073958.1	-	2	538
	AK290194.1	-	2	464
	AK296796.1	-	2	408
	AL136896.1	-	2	450
	BC032862.1	-	2	551	5264754

More Information

Panther Classification:

Molecular Function -

kinase modulator

Gene Ontology Categories:

Process(es)

epidermal growth factor receptor signaling pathway
negative regulation of epidermal growth factor-activated receptor activity
JAK-STAT cascade
negative regulation of signal transduction
cell growth
protein ubiquitination
cytokine-mediated signaling pathway
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of interleukin-6 production
regulation of growth
positive regulation of T-helper 1 cell differentiation
negative regulation of T-helper 2 cell differentiation
negative regulation of JAK-STAT cascade
negative regulation of inflammatory response
negative regulation of monocyte chemotactic protein-1 production
negative regulation of endothelial cell activation

Function(s)

protein kinase inhibitor activity
epidermal growth factor receptor binding
protein binding
receptor tyrosine kinase binding