138578

• Gene Symbol: OPTN
• Gene Name: optineurin
• Gene Aliases: ALS12, FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP
• Chromosome Location: Chr.10: 13100082 - 13138276 on Build GRCh38
• UniGene ID: Hs.332706
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: OPTN
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001008211.1	NP_001008212.1	16	2102
	NM_001008212.1	NP_001008213.1	15	2033
	NM_001008213.1	NP_001008214.1	16	2087
	NM_021980.4	NP_068815.2	14	1881
GenBank mRNA	AF049614.1	-	4	418
	AF061034.1	-	16	1975
	AF420371.1	-	16	1959
	AF420372.1	-	14	1738
	AF420373.1	-	15	1890
	AK055403.1	-	15	2322
	AK122746.1	-	6	1774
	AK303715.1	-	14	1899
	AK316171.1	-	14	1921
	BC013876.2	-	14	1794	3831267
	BC032762.1	-	16	1989	3457195
	KU178502.1	-	13	1649
	KU178503.1	-	6	717

More Information

Gene Ontology Categories:

Process(es)

protein targeting to Golgi
G2/M transition of mitotic cell cycle
negative regulation of receptor recycling
Golgi organization
signal transduction
cell death
macroautophagy
Golgi to plasma membrane protein transport
regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of I-kappaB kinase/NF-kappaB signaling
defense response to Gram-negative bacterium
parkin-mediated mitophagy in response to mitochondrial depolarization
Golgi ribbon formation
xenophagy

Function(s)

protein binding
protein C-terminus binding
Rab GTPase binding
protein binding, bridging
polyubiquitin binding
identical protein binding
K63-linked polyubiquitin binding