138728

• Gene Symbol: STK11
• Gene Name: serine/threonine kinase 11
• Gene Aliases: LKB1, PJS, hLKB1
• Chromosome Location: Chr.19: 1205799 - 1228435 on Build GRCh38
• UniGene ID: Hs.515005
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: STK11
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000455.4	NP_000446.1	2	1431
	XM_005259617.2	XP_005259674.1	2	941
	XM_005259618.3	XP_005259675.1	2	941
	XM_011528209.1	XP_011526511.1	3	1072
GenBank mRNA	AB209553.1	-	2	406
	AF035625.1	-	2	654
	AF217978.1	-	3	1277
	AK314858.1	-	2	442
	BC007981.2	-	2	766	3689780
	BC019334.1	-	2	587	3946005
	EF644172.1	-	2	400
	GU573916.1	-	1	24
	KU178339.1	-	2	316
	U63333.1	-	2	316

More Information

Gene Ontology Categories:

Process(es)

regulation of cell growth
tissue homeostasis
vasculature development
protein phosphorylation
autophagy
cellular response to DNA damage stimulus
cell cycle arrest
spermatid development
axonogenesis
negative regulation of cell proliferation
response to ionizing radiation
positive regulation of autophagy
establishment of cell polarity
regulation of Wnt signaling pathway
negative regulation of cell growth
positive regulation of transforming growth factor beta receptor signaling pathway
activation of protein kinase activity
TCR signalosome assembly
glucose homeostasis
anoikis
positive thymic T cell selection
protein autophosphorylation
regulation of dendrite morphogenesis
positive regulation of peptidyl-tyrosine phosphorylation
positive regulation of axonogenesis
T cell receptor signaling pathway
negative regulation of lipid biosynthetic process
Golgi localization
regulation of protein kinase B signaling
canonical Wnt signaling pathway
negative regulation of epithelial cell proliferation involved in prostate gland development
cellular response to UV-B
positive regulation of protein serine/threonine kinase activity
intrinsic apoptotic signaling pathway by p53 class mediator
dendrite extension
positive regulation of protein localization to nucleus
regulation of signal transduction by p53 class mediator
negative regulation of TORC1 signaling

Function(s)

magnesium ion binding
p53 binding
protein serine/threonine kinase activity
protein binding
ATP binding
LRR domain binding
protein kinase activator activity