138852

• Gene Symbol: TGFB2
• Gene Name: transforming growth factor beta 2
• Gene Aliases: LDS4, TGF-beta2
• Chromosome Location: Chr.1: 218345334 - 218444619 on Build GRCh38
• UniGene ID: Hs.133379
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TGFB2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001135599.2	NP_001129071.1	5	2107
	NM_003238.3	NP_003229.1	4	2023
GenBank mRNA	AK295671.1	-	5	586
	AK296504.1	-	5	740
	AK299839.1	-	4	363
	AK313106.1	-	4	760
	BC096235.4	-	4	809	40005424
	BC096236.4	-	4	813
	BC099635.1	-	4	813	40005426
	M19154.1	-	5	1206
	Y00083.1	-	4	836

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031131, XM_006250448, AJ132718, AF153013, AF135598, and others.

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

cell morphogenesis
cartilage condensation
angiogenesis
eye development
response to hypoxia
epithelial to mesenchymal transition
hair follicle development
blood vessel remodeling
platelet degranulation
heart morphogenesis
outflow tract septum morphogenesis
membranous septum morphogenesis
heart valve morphogenesis
atrioventricular valve morphogenesis
pulmonary valve morphogenesis
endocardial cushion morphogenesis
cardiac right ventricle morphogenesis
ventricular trabecula myocardium morphogenesis
endocardial cushion fusion
atrial septum primum morphogenesis
protein phosphorylation
cell cycle arrest
transforming growth factor beta receptor signaling pathway
SMAD protein import into nucleus
cell-cell signaling
axon guidance
salivary gland morphogenesis
heart development
cell death
cell proliferation
positive regulation of cell proliferation
negative regulation of cell proliferation
glial cell migration
response to wounding
embryo development
cardioblast differentiation
positive regulation of gene expression
negative regulation of gene expression
positive regulation of epithelial cell migration
negative regulation of alkaline phosphatase activity
positive regulation of epithelial to mesenchymal transition
positive regulation of pathway-restricted SMAD protein phosphorylation
negative regulation of macrophage cytokine production
positive regulation of phosphatidylinositol 3-kinase signaling
cell growth
cell migration
signal transduction by protein phosphorylation
hemopoiesis
collagen fibril organization
positive regulation of cell growth
negative regulation of cell growth
neutrophil chemotaxis
hair follicle morphogenesis
activation of protein kinase activity
response to progesterone
positive regulation of stress-activated MAPK cascade
regulation of transforming growth factor beta2 production
regulation of actin cytoskeleton organization
positive regulation of cell adhesion mediated by integrin
ascending aorta morphogenesis
wound healing
dopamine biosynthetic process
odontogenesis
response to drug
catagen
uterine wall breakdown
positive regulation of neuron apoptotic process
cell-cell junction organization
positive regulation of integrin biosynthetic process
positive regulation of ossification
positive regulation of cell cycle
positive regulation of heart contraction
negative regulation of Ras protein signal transduction
somatic stem cell division
embryonic digestive tract development
neuron fate commitment
neuron development
generation of neurons
negative regulation of epithelial cell proliferation
positive regulation of protein secretion
negative regulation of immune response
positive regulation of immune response
positive regulation of cell division
positive regulation of catagen
positive regulation of cardioblast differentiation
cardiac muscle cell proliferation
cardiac epithelial to mesenchymal transition
face morphogenesis
pathway-restricted SMAD protein phosphorylation
SMAD protein signal transduction
ventricular septum morphogenesis
atrial septum morphogenesis
negative regulation of cartilage development
pharyngeal arch artery morphogenesis
positive regulation of activation-induced cell death of T cells
positive regulation of extracellular matrix disassembly
extrinsic apoptotic signaling pathway
positive regulation of protein localization to nucleus
regulation of apoptotic process involved in outflow tract morphogenesis
regulation of complement-dependent cytotoxicity
positive regulation of GTP binding
negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

beta-amyloid binding
receptor signaling protein serine/threonine kinase activity
receptor binding
type II transforming growth factor beta receptor binding
cytokine activity
transforming growth factor beta receptor binding
protein binding
growth factor activity
type III transforming growth factor beta receptor binding
protein homodimerization activity
protein heterodimerization activity