140334

• Gene Symbol: CNOT1
• Gene Name: CCR4-NOT transcription complex subunit 1
• Gene Aliases: AD-005, CDC39, NOT1, NOT1H
• Chromosome Location: Chr.16: 58519946 - 58629886 on Build GRCh38
• UniGene ID: Hs.460923
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CNOT1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001265612.1	NP_001252541.1	29	4193
	NM_016284.4	NP_057368.3	29	4208
	NM_206999.2	NP_996882.1	29	4208
	NR_049763.1		29	4193
GenBank mRNA	AB023224.2	-	16	2253
	AK302495.1	-	6	578
	AL117492.1	-	1	47
	AL832769.1	-	29	4157
	AL833549.1	-	29	4167
	BC024317.1	-	12	1607
	BC040523.1	-	29	4160	5266600
	BX537840.1	-	29	4139
	BX647815.1	-	29	4148
	CR749237.1	-	22	3148
	EF553522.1	-	29	4142

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_153164, NM_178078, NM_001205226, BC018281, BC157948, and others.

Panther Classification:

Molecular Function -

mRNA polyadenylation factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
nuclear-transcribed mRNA poly(A) tail shortening
transcription, DNA-templated
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
multicellular organism development
positive regulation of cytoplasmic mRNA processing body assembly
negative regulation of translation
negative regulation of intracellular estrogen receptor signaling pathway
gene silencing by miRNA
negative regulation of retinoic acid receptor signaling pathway
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
positive regulation of mRNA catabolic process
RNA phosphodiester bond hydrolysis, exonucleolytic
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
regulation of stem cell population maintenance

Function(s)

poly(A)-specific ribonuclease activity
protein binding
protein domain specific binding
estrogen receptor binding
protein complex scaffold
retinoic acid receptor binding
poly(A) RNA binding
armadillo repeat domain binding