14060

• Gene Symbol: B2M
• Gene Name: beta-2-microglobulin
• Gene Aliases: IMD43
• Chromosome Location: Chr.15: 44711487 - 44718159 on Build GRCh38
• UniGene ID: Hs.534255
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: B2M
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_004048.2	NP_004039.1	2	152
	XM_005254549.3	XP_005254606.1	2	147
GenBank mRNA	AB021288.1	-	2	105
	AF072097.1	-		892
	AK303560.1	-	2	122
	AK315776.1	-	2	122
	AY007153.1	-	2	104
	AY187687.1	-	2	92
	BC032589.1	-	2	126	5502428
	BC064910.1	-	2	109	6055473
	BU658737.1	-	2	164
	CR457066.1	-	2	92
	DQ839493.1	-	2	92
	DQ839494.1	-	2	92
	DQ884406.1	-	2, 3	92
	S54761.1	-	2	117
	S82297.1	-	2	112
	V00567.1	-	2	65
	X07621.1	-	2	107

More Information

Panther Classification:

Molecular Function -

major histocompatibility complex protein

Gene Ontology Categories:

Process(es)

retina homeostasis
positive regulation of T cell mediated cytotoxicity
antigen processing and presentation of peptide antigen via MHC class I
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
positive regulation of T cell cytokine production
regulation of membrane depolarization
negative regulation of neuron projection development
antibacterial humoral response
antigen processing and presentation of endogenous peptide antigen via MHC class I
positive regulation of protein binding
T cell differentiation in thymus
protein refolding
response to drug
cellular protein metabolic process
innate immune response
response to cadmium ion
positive regulation of receptor-mediated endocytosis
regulation of defense response to virus by virus
regulation of immune response
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
iron ion homeostasis
interferon-gamma-mediated signaling pathway
cellular response to lipopolysaccharide
cellular response to iron ion
negative regulation of receptor binding
positive regulation of receptor binding
positive regulation of ferrous iron import into cell
positive regulation of ferrous iron binding
positive regulation of transferrin receptor binding

Function(s)

glycoprotein binding
protein binding
identical protein binding