142

• Gene Symbol: ACVR2A
• Gene Name: activin A receptor type 2A
• Gene Aliases: ACTRII, ACVR2
• Chromosome Location: Chr.2: 147844517 - 147930827 on Build GRCh38
• UniGene ID: Hs.470174
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ACVR2A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001278579.1	NP_001265508.1	3	506
	NM_001278580.1	NP_001265509.1	2	309
	NM_001616.4	NP_001607.1	2	395
GenBank mRNA	AK301629.1	-	2	309
	AK314124.1	-	2	585
	BC067417.1	-	2	323	7002204
	BC067418.1	-	2	323	7002205
	BC069707.1	-	2	390	7262543
	D31770.1	-	2	400
	M93415.1	-	3	410
	X62381.1	-	2	382
	X63128.1	-	2	252

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031571, XM_008761703, S48190, L10639.
This siRNA also targets the following transcripts in Mouse: NM_007396, AK041246, AK143186, M65287, BC138823.

Panther Classification:

Molecular Function -

serine/threonine protein kinase receptor

Gene Ontology Categories:

Process(es)

gastrulation with mouth forming second
positive regulation of protein phosphorylation
transmembrane receptor protein serine/threonine kinase signaling pathway
spermatogenesis
determination of left/right symmetry
mesoderm development
anterior/posterior pattern specification
positive regulation of pathway-restricted SMAD protein phosphorylation
signal transduction by protein phosphorylation
positive regulation of bone mineralization
BMP signaling pathway
regulation of BMP signaling pathway
activin receptor signaling pathway
positive regulation of activin receptor signaling pathway
sperm ejaculation
penile erection
positive regulation of erythrocyte differentiation
positive regulation of osteoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
embryonic skeletal system development
regulation of nitric-oxide synthase activity
Sertoli cell proliferation
cellular response to BMP stimulus

Function(s)

protein serine/threonine kinase activity
transmembrane receptor protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
protein binding
ATP binding
coreceptor activity
activin-activated receptor activity
growth factor binding
PDZ domain binding
inhibin binding
protein self-association
metal ion binding
activin binding
BMP receptor activity