142621

• Gene Symbol: SHC1
• Gene Name: SHC adaptor protein 1
• Gene Aliases: SHC, SHCA
• Chromosome Location: Chr.1: 154962298 - 154974492 on Build GRCh38
• UniGene ID: Hs.433795
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SHC1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001130040.1	NP_001123512.1	5	991
	NM_001130041.1	NP_001123513.1	6	679
	NM_001202859.1	NP_001189788.1	6	679
	NM_003029.4	NP_003020.2	6	679
	NM_183001.4	NP_892113.4	5	991
	XM_005245449.4	XP_005245506.1	5	2207
	XM_005245451.4	XP_005245508.1	6	602
	XM_011509892.2	XP_011508194.1	5	2204
	XM_011509893.2	XP_011508195.1	5	2205
	XM_011509898.2	XP_011508200.1	5	520
GenBank mRNA	AB208849.1	-	2	108
	AB451255.1	-	5	770
	AB451379.1	-	5	770
	AK096169.1	-	5	974
	AK130014.1	-	4	324
	AK225332.1	-	5	916
	AK292143.1	-	6	679
	AK296786.1	-	6	802
	AK315842.1	-	6	590
	BC014158.2	-	6	560	4541216
	BC033925.1	-	3	393	4896385
	BX647136.1	-	6	907
	BX647149.1	-	5	991
	U73377.1	-	5	964
	X68148.1	-	6	521

More Information

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPK activity
angiogenesis
response to hypoxia
epidermal growth factor receptor signaling pathway
regulation of epidermal growth factor-activated receptor activity
Ras protein signal transduction
heart development
aging
positive regulation of cell proliferation
insulin receptor signaling pathway
response to toxic substance
viral process
single organismal cell-cell adhesion
organ regeneration
neuron projection development
actin cytoskeleton reorganization
response to nicotine
IRE1-mediated unfolded protein response
Fc-epsilon receptor signaling pathway
ERBB2 signaling pathway
regulation of growth
response to hydrogen peroxide
positive regulation of GTPase activity
positive regulation of DNA replication
positive regulation of vasoconstriction
positive regulation of smooth muscle cell proliferation
leukocyte migration
response to glucocorticoid
cellular response to growth factor stimulus

Function(s)

phosphotyrosine binding
transmembrane receptor protein tyrosine kinase adaptor activity
Ras guanyl-nucleotide exchange factor activity
epidermal growth factor receptor binding
insulin receptor binding
insulin-like growth factor receptor binding
neurotrophin TRKA receptor binding
protein binding
phospholipid binding
ephrin receptor binding
protein phosphatase 2A binding