142826

• Gene Symbol: SIAH2
• Gene Name: siah E3 ubiquitin protein ligase 2
• Gene Aliases: hSiah2
• Chromosome Location: Chr.3: 150741123 - 150763476 on Build GRCh38
• UniGene ID: Hs.477959
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SIAH2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005067.5	NP_005058.3	1	929
GenBank mRNA	AK223565.1	-	1	578
	BC013082.2	-	1	631	4153095
	U76248.1	-	1	828
	Y15268.1	-	1	302

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_134457, AB067815, AF389477.
This siRNA also targets the following transcripts in Mouse: NM_009174, AK139626, Z19581, AK149316, BC058400.

Panther Classification:

Molecular Function -

ubiquitin-protein ligase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

protein polyubiquitination
ubiquitin-dependent protein catabolic process
apoptotic process
cell cycle
small GTPase mediated signal transduction
axon guidance
regulation of protein ubiquitination
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
cellular protein catabolic process
cellular protein metabolic process
negative regulation of canonical Wnt signaling pathway
negative regulation of nucleic acid-templated transcription
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

transcription corepressor activity
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
ubiquitin conjugating enzyme binding
ubiquitin protein ligase activity