143091

• Gene Symbol: SPAST
• Gene Name: spastin
• Gene Aliases: ADPSP, FSP2, SPG4
• Chromosome Location: Chr.2: 32063551 - 32157637 on Build GRCh38
• UniGene ID: Hs.468091
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SPAST
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_014946.3	NP_055761.2	2	662
	NM_199436.1	NP_955468.1	2	662
	XM_005264516.4	XP_005264573.1	2	438
	XM_011533067.2	XP_011531369.1	2	722
	XM_017004777.1	XP_016860266.1	2	719
	XM_017004778.1	XP_016860267.1	2	722
GenBank mRNA	AB029006.1	-	2	662
	AJ246001.1	-	2	566
	BC150260.1	-	2	662	9007202

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001108702, XM_008764486, XM_008764487, XM_008764488, BC166846.
This siRNA also targets the following transcripts in Mouse: NM_016962, NM_001162870, AJ246002, AK044900, BC046286, and others.

Panther Classification:

Molecular Function -

non-motor microtubule binding protein

Gene Ontology Categories:

Process(es)

mitotic cytokinesis
microtubule bundle formation
ER to Golgi vesicle-mediated transport
axonogenesis
anterograde axonal transport
metabolic process
exit from mitosis
axonal transport of mitochondrion
positive regulation of microtubule depolymerization
cytoplasmic microtubule organization
nuclear envelope reassembly
positive regulation of cytokinesis
cytokinetic process
protein hexamerization
microtubule severing
mitotic spindle disassembly
protein homooligomerization
membrane fission

Function(s)

protein binding
ATP binding
microtubule binding
microtubule-severing ATPase activity
alpha-tubulin binding
beta-tubulin binding