143245

• Gene Symbol: MYOC
• Gene Name: myocilin
• Gene Aliases: GLC1A, GPOA, JOAG, JOAG1, TIGR
• Chromosome Location: Chr.1: 171635417 - 171652633 on Build GRCh38
• UniGene ID: Hs.436037
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MYOC
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000261.1	NP_000252.1	2	717
GenBank mRNA	AF001620.1	-	2	717
	AK097310.1	-	3	665
	AK300924.1	-	3	593
	AK300943.1	-	3	718
	AK301297.1	-	3	638
	AK315443.1	-	2	767
	BC029261.1	-	2	755	5179076
	D88214.1	-	2	759
	FJ227302.1	-	2	717
	FJ237046.1	-	2	717
	FJ237047.1	-	2	717
	KU178210.1	-	2	695
	U85257.1	-	2	731

More Information

Panther Classification:

Molecular Function -

structural protein

Gene Ontology Categories:

Process(es)

osteoblast differentiation
negative regulation of cell-matrix adhesion
positive regulation of phosphatidylinositol 3-kinase signaling
skeletal muscle hypertrophy
myelination in peripheral nervous system
positive regulation of cell migration
neuron projection development
negative regulation of Rho protein signal transduction
non-canonical Wnt signaling pathway via JNK cascade
ERBB2-ERBB3 signaling pathway
regulation of MAPK cascade
clustering of voltage-gated sodium channels
positive regulation of stress fiber assembly
negative regulation of stress fiber assembly
positive regulation of focal adhesion assembly
positive regulation of protein kinase B signaling
positive regulation of mitochondrial depolarization
bone development
positive regulation of substrate adhesion-dependent cell spreading

Function(s)

fibronectin binding
frizzled binding
protein binding
receptor tyrosine kinase binding
myosin light chain binding
metal ion binding