143288

• Gene Symbol: PKD2
• Gene Name: polycystin 2, transient receptor potential cation channel
• Gene Aliases: APKD2, PC2, PKD4, Pc-2, TRPP2
• Chromosome Location: Chr.4: 88007647 - 88077779 on Build GRCh38
• UniGene ID: Hs.181272
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PKD2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000297.3	NP_000288.1	15	3069
	XM_011532028.2	XP_011530330.1	14	2837
	XM_011532029.1	XP_011530331.1	15	2359
	XM_011532030.2	XP_011530332.1	13	2400
GenBank mRNA	AF054992.1	-	1	195
	AK293461.1	-	8	1234
	AK294173.1	-	10	1631
	AK294589.1	-	7	1460
	U50928.1	-	15	3048
	U56813.1	-	12	1903

More Information

Panther Classification:

Molecular Function -

ion channel

Gene Ontology Categories:

Process(es)

branching involved in ureteric bud morphogenesis
liver development
embryonic placenta development
heart looping
detection of nodal flow
calcium ion transport
cell cycle arrest
JAK-STAT cascade
determination of left/right symmetry
heart development
negative regulation of cell proliferation
spinal cord development
neural tube development
regulation of cAMP metabolic process
positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
cellular response to reactive oxygen species
metanephric part of ureteric bud development
sodium ion transmembrane transport
aorta development
regulation of cell proliferation
cytoplasmic sequestering of transcription factor
positive regulation of nitric oxide biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
detection of mechanical stimulus
release of sequestered calcium ion into cytosol
centrosome duplication
regulation of postsynaptic membrane potential
negative regulation of ryanodine-sensitive calcium-release channel activity
placenta blood vessel development
renal tubule morphogenesis
renal artery morphogenesis
calcium ion transmembrane transport
positive regulation of cell cycle arrest
cellular response to hydrostatic pressure
cellular response to osmotic stress
cellular response to fluid shear stress
potassium ion transmembrane transport
determination of liver left/right asymmetry
metanephric mesenchyme development
mesonephric tubule development
mesonephric duct development
metanephric smooth muscle tissue development
metanephric cortex development
metanephric ascending thin limb development
metanephric cortical collecting duct development
metanephric distal tubule development
metanephric S-shaped body morphogenesis
regulation of calcium ion import
negative regulation of G1/S transition of mitotic cell cycle

Function(s)

receptor binding
voltage-gated ion channel activity
voltage-gated calcium channel activity
voltage-gated sodium channel activity
potassium channel activity
calcium ion binding
protein binding
cytoskeletal protein binding
voltage-gated cation channel activity
identical protein binding
protein homodimerization activity
actinin binding
HLH domain binding
ion channel binding
calcium-induced calcium release activity
ATPase binding
phosphoprotein binding
muscle alpha-actinin binding