143549

• Gene Symbol: MAP3K11
• Gene Name: mitogen-activated protein kinase kinase kinase 11
• Gene Aliases: MEKK11, MLK-3, MLK3, PTK1, SPRK
• Chromosome Location: Chr.11: 65597755 - 65614338 on Build GRCh38
• UniGene ID: Hs.502872
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MAP3K11
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002419.3	NP_002410.1	10	3175
GenBank mRNA	AK057256.1	-	5	1415
	AK090614.1	-	9	1744
	AK222781.1	-	10	3168
	AK299609.1	-	10	2204
	AK316032.1	-	10	2044
	BC011263.2	-	10	3163	4215281
	BC064543.1	-	10	3134	5733866
	L32976.1	-	10	3163
	U07747.1	-	10	3132

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001013150, BC081952, AY240868.
This siRNA also targets the following transcripts in Mouse: NM_022012, BC095963, BC047152, AK212358, BC030928, and others.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

activation of MAPK activity
protein phosphorylation
microtubule-based process
JNK cascade
activation of JNKK activity
activation of JUN kinase activity
cell death
cell proliferation
positive regulation of JUN kinase activity
positive regulation of neuron apoptotic process
positive regulation of JNK cascade
protein autophosphorylation

Function(s)

protein kinase activity
protein serine/threonine kinase activity
JUN kinase kinase kinase activity
protein binding
ATP binding
mitogen-activated protein kinase kinase binding
mitogen-activated protein kinase kinase kinase binding
identical protein binding
protein homodimerization activity
Rac GTPase binding