143736

• Gene Symbol: PDE2A
• Gene Name: phosphodiesterase 2A
• Gene Aliases: CGS-PDE, PDE2A1, PED2A4, cGSPDE
• Chromosome Location: Chr.11: 72576140 - 72674453 on Build GRCh38
• UniGene ID: Hs.503163
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PDE2A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001143839.3	NP_001137311.1	30	3410
	NM_001146209.2	NP_001139681.1	32	3460
	NM_001243784.1	NP_001230713.1	31	3472
	NM_002599.4	NP_002590.1	31	3593
	XM_005274040.2	XP_005274097.1	31	3416
	XM_011545096.2	XP_011543398.1	28	3110
	XM_017017910.1	XP_016873399.1	27	3826
GenBank mRNA	AK092278.1	-	27	2365
	AK131525.1	-	21	2634
	BC040974.1	-	31	3564	5285017
	U67733.1	-	31	3505

More Information

Panther Classification:

Molecular Function -

phosphodiesterase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
cAMP catabolic process
protein targeting to mitochondrion
metabolic process
cAMP-mediated signaling
cGMP-mediated signaling
negative regulation of cAMP biosynthetic process
negative regulation of protein import into nucleus, translocation
cellular response to drug
cellular response to macrophage colony-stimulating factor stimulus
negative regulation of vascular permeability
positive regulation of vascular permeability
cGMP catabolic process
positive regulation of inflammatory response
establishment of endothelial barrier
calcium ion transmembrane transport
cellular response to mechanical stimulus
cellular response to cGMP
cellular response to transforming growth factor beta stimulus

Function(s)

cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-AMP phosphodiesterase activity
cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
calcium channel activity
protein binding
drug binding
cAMP binding
cGMP binding
TPR domain binding
protein homodimerization activity
metal ion binding
3',5'-cyclic-GMP phosphodiesterase activity