144067

• Gene Symbol: MEF2A
• Gene Name: myocyte enhancer factor 2A
• Gene Aliases: ADCAD1, RSRFC4, RSRFC9, mef2
• Chromosome Location: Chr.15: 99565455 - 99716488 on Build GRCh38
• UniGene ID: Hs.268675
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MEF2A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005587.3	NP_005578.2	5	709
	XM_005254914.2	XP_005254971.1	5	674
	XM_005254916.3	XP_005254973.1	5	674
	XM_011521571.2	XP_011519873.1	5	674
	XM_011521572.2	XP_011519874.1	5	619
	XM_011521573.2	XP_011519875.1	5	649
	XM_011521576.2	XP_011519878.1	4	563
	XM_011521577.2	XP_011519879.1	4	497
	XM_011521578.2	XP_011519880.1	4	1156
	XM_011521579.2	XP_011519881.1	4	573
	XM_011521581.2	XP_011519883.1	5	937
	XM_011521582.2	XP_011519884.1	6	1142
	XM_011521585.2	XP_011519887.1	4	733
	XM_011521590.2	XP_011519892.1	5	674
	XM_017022190.1	XP_016877679.1	4	563
	XM_017022191.1	XP_016877680.1	4	555
	XM_017022192.1	XP_016877681.1	4	552
	XM_017022193.1	XP_016877682.1	5	747
	XM_017022194.1	XP_016877683.1	4	563
	XM_017022195.1	XP_016877684.1	4	420
	XM_017022196.1	XP_016877685.1	6	1063
	XM_017022197.1	XP_016877686.1	5	2854
	XM_017022198.1	XP_016877687.1	6	1063
	XM_017022199.1	XP_016877688.1	4	1352
	XM_017022200.1	XP_016877689.1	5	1134
	XM_017022201.1	XP_016877690.1	4	757
	XM_017022203.1	XP_016877692.1	5	937
GenBank mRNA	BC013437.2	-	5	627	3896491
	KU178181.1	-	3	308
	KU178182.1	-	3	308
	X63381.1	-	4	536
	X68505.1	-	5	722

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001014035, XM_008759542, XM_008759540, DQ323505, GU646868, and others.
This siRNA also targets the following transcripts in Mouse: NM_001291191, NM_001291192, AK040227, BC096598, AK153751.

Panther Classification:

Molecular Function -

MADS box transcription factor

Gene Ontology Categories:

Process(es)

mitochondrial genome maintenance
negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
transcription, DNA-templated
transcription from RNA polymerase II promoter
apoptotic process
heart development
muscle organ development
positive regulation of cardiac muscle hypertrophy
positive regulation of transcription from RNA polymerase II promoter
mitochondrion distribution
dendrite morphogenesis
positive regulation of muscle cell differentiation
ventricular cardiac myofibril assembly
cardiac conduction
ERK5 cascade
cellular response to calcium ion

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
RNA polymerase II transcription coactivator activity
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
protein kinase binding
activating transcription factor binding
histone acetyltransferase binding
histone deacetylase binding
sequence-specific DNA binding
SMAD binding
protein heterodimerization activity