144250 Validated

• Gene Symbol: PIK3CA
• Gene Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
• Gene Aliases: CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, PI3K-alpha, p110-alpha
• Chromosome Location: Chr.3: 179148114 - 179240093 on Build GRCh38
• UniGene ID: Hs.553498
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PIK3CA
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_006218.3	NP_006209.2	2	475
	XM_006713658.3	XP_006713721.1	2	500
	XM_011512894.2	XP_011511196.1	2	581
GenBank mRNA	AB210020.1	-	1	323
	AK292940.1	-	2	433
	AK302608.1	-	1	153
	BC113601.1	-	1	395	8322653
	BC113603.1	-	1	395	8322655
	BX473473.1	-	1	239
	U79143.1	-	1	318
	Z29090.1	-	1	330

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_008839, BC089038, BC130228, U03279.

Matching Taqman Gene Expression Assay:

Hs00180679_m1

Panther Classification:

Molecular Function -

kinase

Gene Ontology Categories:

Process(es)

angiogenesis
liver development
vasculature development
glucose metabolic process
protein phosphorylation
phosphatidylinositol biosynthetic process
epidermal growth factor receptor signaling pathway
regulation of gene expression
regulation of phosphatidylinositol 3-kinase signaling
platelet activation
T cell costimulation
activation of protein kinase activity
positive regulation of peptidyl-serine phosphorylation
phosphatidylinositol-3-phosphate biosynthetic process
insulin receptor signaling pathway via phosphatidylinositol 3-kinase
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
ERBB2 signaling pathway
regulation of multicellular organism growth
regulation of cellular respiration
protein kinase B signaling
negative regulation of neuron apoptotic process
endothelial cell migration
hypomethylation of CpG island
phosphatidylinositol phosphorylation
vascular endothelial growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
T cell receptor signaling pathway
leukocyte migration
cardiac muscle contraction
adipose tissue development
cellular response to glucose stimulus
energy homeostasis
mitophagy in response to mitochondrial depolarization
negative regulation of fibroblast apoptotic process
regulation of genetic imprinting
negative regulation of anoikis

Function(s)

protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
1-phosphatidylinositol-3-kinase activity
protein kinase activator activity
phosphatidylinositol 3-kinase activity
1-phosphatidylinositol-4-phosphate 3-kinase activity
insulin receptor substrate binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity