144357

• Gene Symbol: PMAIP1
• Gene Name: phorbol-12-myristate-13-acetate-induced protein 1
• Gene Aliases: APR, NOXA
• Chromosome Location: Chr.18: 59899960 - 59904306 on Build GRCh38
• UniGene ID: Hs.96
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PMAIP1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_021127.2	NP_066950.1	2	1841
GenBank mRNA	D90070.1	-	2	1791

More Information

Gene Ontology Categories:

Process(es)

release of cytochrome c from mitochondria
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
response to UV
response to X-ray
proteasomal protein catabolic process
positive regulation of glucose metabolic process
negative regulation of mitochondrial membrane potential
positive regulation of protein oligomerization
cellular response to glucose starvation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
regulation of apoptotic process
T cell homeostasis
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
response to dsRNA
positive regulation of DNA damage response, signal transduction by p53 class mediator
positive regulation of neuron apoptotic process
regulation of mitochondrial membrane permeability
negative regulation of fibroblast proliferation
defense response to virus
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to hypoxia
intrinsic apoptotic signaling pathway by p53 class mediator
reactive oxygen species metabolic process
positive regulation of release of cytochrome c from mitochondria
intrinsic apoptotic signaling pathway
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of intrinsic apoptotic signaling pathway

Function(s)

protein binding