144569

• Gene Symbol: IL4
• Gene Name: interleukin 4
• Gene Aliases: BCGF-1, BCGF1, BSF-1, BSF1, IL-4
• Chromosome Location: Chr.5: 132673986 - 132682678 on Build GRCh38
• UniGene ID: Hs.73917
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: IL4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000589.3	NP_000580.1	3	379
	NM_172348.2	NP_758858.1	2	331
GenBank mRNA	AB102862.1	-	2	266
	AF043336.1	-	2	197
	BC066278.1	-	3	379
	BC067514.1	-	3	379	6971780
	BC067515.1	-	3	379	6971782
	BC070123.1	-	3	376	30415895
	CD640452.1	-	3	379
	EF173851.1	-	2	184
	JX878389.1	-	4	415
	M13982.1	-	3	377
	X81851.1	-	2	266

More Information

Panther Classification:

Molecular Function -

interleukin superfamily

Gene Ontology Categories:

Process(es)

microglial cell activation
innate immune response in mucosa
positive regulation of defense response to virus by host
T-helper 1 cell lineage commitment
negative regulation of acute inflammatory response
negative regulation of chronic inflammatory response
chemotaxis
immune response
cellular defense response
female pregnancy
response to nutrient
cholesterol metabolic process
regulation of proton transport
negative regulation of epithelial cell migration
response to organic cyclic compound
B cell differentiation
positive regulation of B cell proliferation
B cell costimulation
positive regulation of interleukin-10 production
positive regulation of interleukin-13 production
response to cytokine
T-helper 2 cell cytokine production
type 2 immune response
positive regulation of T cell proliferation
positive regulation of activated T cell proliferation
regulation of phosphorylation
response to drug
positive regulation of tyrosine phosphorylation of Stat5 protein
defense response to protozoan
myeloid dendritic cell differentiation
negative regulation of macrophage activation
negative regulation of apoptotic process
positive regulation of mast cell degranulation
negative regulation of nitric oxide biosynthetic process
T-helper 2 cell differentiation
positive regulation of chemokine biosynthetic process
connective tissue growth factor biosynthetic process
regulation of isotype switching
positive regulation of MHC class II biosynthetic process
response to ethanol
positive regulation of T cell differentiation
negative regulation of osteoclast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of isotype switching to IgE isotypes
positive regulation of isotype switching to IgG isotypes
regulation of immune response
positive regulation of sequence-specific DNA binding transcription factor activity
retina development in camera-type eye
negative regulation of white fat cell proliferation
cellular response to mercury ion
positive regulation of mononuclear cell migration
dendritic cell differentiation
extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of myoblast fusion
negative regulation of complement-dependent cytotoxicity
negative regulation of T-helper 17 cell differentiation
negative regulation of endothelial cell apoptotic process
positive regulation of eosinophil chemotaxis
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

cytokine activity
interleukin-4 receptor binding
protein binding
growth factor activity