144672

Gene Symbol:

FOXO3 FOXO3B

Gene Name:

forkhead box O3

forkhead box O3B pseudogene

Gene Aliases:

AF6q21, FKHRL1, FKHRL1P2, FOXO2, FOXO3A

FKHRL1P1, ZNF286C

Chromosome Location:

Chr.6: 108559823 - 108684769 on Build GRCh38

Chromosome Location:

Chr.17: 18665923 - 18673181 on Build GRCh38

UniGene ID:

Hs.220950

Hs.592126

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: FOXO3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001455.3	NP_001446.1	2	1417
	NM_201559.2	NP_963853.1	3	1390
	XM_005266867.4	XP_005266924.1	3	638
	XM_005266868.3	XP_005266925.1	2	662
	XM_011535626.1	XP_011533928.1	2	588
	XM_011535628.2	XP_011533930.1	2	4946
	XM_011535629.2	XP_011533931.1	2	611
	XM_017010585.1	XP_016866074.1	3	2323
	XM_017010586.1	XP_016866075.1	2	2206
GenBank mRNA	AF032886.1	-	2	1998
	AK092357.1	-	3	778
	AK122861.1	-	3	973
	AK301304.1	-	2	579
	AK303933.1	-	2	563
	AK311587.1	-	2	677
	BC020227.1	-	3	1378	4111403
	BC021224.2	-	3	1378	4137370
	BC068552.1	-	2	1417	30347471

Gene Symbol: FOXO3B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_026718.1		1	1329

More Information

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
ovulation from ovarian follicle
initiation of primordial ovarian follicle growth
antral ovarian follicle growth
oocyte maturation
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
regulation of translation
DNA damage response, signal transduction by p53 class mediator
tumor necrosis factor-mediated signaling pathway
cellular response to oxidative stress
glucose homeostasis
positive regulation of apoptotic process
positive regulation of neuron apoptotic process
positive regulation of erythrocyte differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of canonical Wnt signaling pathway
neuronal stem cell population maintenance
extrinsic apoptotic signaling pathway in absence of ligand
regulation of neural precursor cell proliferation
regulation of reactive oxygen species metabolic process

Function(s)

core promoter binding
transcription cofactor binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
beta-catenin binding
protein kinase binding
chromatin DNA binding
sequence-specific DNA binding