144692

• Gene Symbol: XRCC6
• Gene Name: X-ray repair cross complementing 6
• Gene Aliases: CTC75, CTCBF, G22P1, KU70, ML8, TLAA
• Chromosome Location: Chr.22: 41621163 - 41664048 on Build GRCh38
• UniGene ID: Hs.292493
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: XRCC6
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001288976.1	NP_001275905.1	5	660
	NM_001288977.1	NP_001275906.1	5	651
	NM_001288978.1	NP_001275907.1	4	661
	NM_001469.4	NP_001460.1	5	774
GenBank mRNA	AK055786.1	-	5	519
	AK293439.1	-	4	508
	AK304580.1	-	4	517
	AK315618.1	-	5	668
	BC001583.1	-	2	324
	BC008343.1	-	4	1231	3509801
	BC010034.2	-	5	615	3536083
	BC012154.2	-	4	592	4561541
	BC018259.2	-	5	614	3448510
	BC072449.1	-	4	598	6167735
	BQ217843.1	-	1	257
	BU902323.1	-	5	665
	CR542219.1	-	4	576
	J04607.1	-	4	593
	J04611.1	-	5	609
	M32865.1	-	4	600
	S38729.1	-	4	600

More Information

Panther Classification:

Molecular Function -

DNA helicase

Gene Ontology Categories:

Process(es)

telomere maintenance
DNA ligation
double-strand break repair via nonhomologous end joining
DNA recombination
transcription, DNA-templated
positive regulation of type I interferon production
DNA duplex unwinding
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of smooth muscle cell proliferation
protein heterotetramerization
cellular response to gamma radiation
cellular response to X-ray
establishment of integrated proviral latency
double-strand break repair via classical nonhomologous end joining

Function(s)

DNA binding
damaged DNA binding
double-stranded DNA binding
double-stranded telomeric DNA binding
ATP-dependent DNA helicase activity
protein binding
ATP binding
protein C-terminus binding
transcription regulatory region DNA binding
poly(A) RNA binding
macromolecular complex binding
5'-deoxyribose-5-phosphate lyase activity