145248

Gene Symbol:

HSPA1B HSPA1A

Gene Name:

heat shock protein family A (Hsp70) member 1B

heat shock protein family A (Hsp70) member 1A

Gene Aliases:

HSP70-1B, HSP70-2, HSP70.2

HEL-S-103, HSP70-1, HSP70-1A, HSP70.1, HSP70I, HSP72, HSPA1

Chromosome Location:

Chr.6: 31827735 - 31830254 on Build GRCh38

Chromosome Location:

Chr.6: 31815514 - 31817942 on Build GRCh38

UniGene ID:

Hs.274402

Hs.274402

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: HSPA1B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005346.4	NP_005337.2	1	2276
GenBank mRNA	AK303967.1	-	2	2001
	AL360193.1	-	1	399
	BC009322.2	-	1	2100	4123837
	BC057397.1	-	1	2257	6188453
	BC063507.1	-	1	2263	4153196

Gene Symbol: HSPA1A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	BC018740.1	-	1	2167	4906865

More Information

Gene Ontology Categories:

Process(es)

positive regulation of gene expression
regulation of cell death
regulation of protein ubiquitination
negative regulation of protein ubiquitination
positive regulation of interleukin-8 production
cellular response to oxidative stress
cellular response to heat
protein refolding
ATP metabolic process
viral entry into host cell
protein stabilization
positive regulation of NF-kappaB transcription factor activity
negative regulation of cell death
cellular heat acclimation
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
negative regulation of inclusion body assembly
regulation of cellular response to heat
positive regulation of tumor necrosis factor-mediated signaling pathway
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

virus receptor activity
G-protein coupled receptor binding
receptor binding
protein binding
ATP binding
ATPase activity
enzyme binding
heat shock protein binding
ubiquitin protein ligase binding
ATPase activity, coupled
histone deacetylase binding
protein binding involved in protein folding
unfolded protein binding
C3HC4-type RING finger domain binding