145254

• Gene Symbol: RBPJ
• Gene Name: recombination signal binding protein for immunoglobulin kappa J region
• Gene Aliases: AOS3, CBF1, IGKJRB, IGKJRB1, KBF2, RBP-J, RBPJK, RBPSUH, SUH, csl
• Chromosome Location: Chr.4: 26163489 - 26435131 on Build GRCh38
• UniGene ID: Hs.479396
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: RBPJ
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005349.3	NP_005340.2	3, 4	332
	NM_015874.4	NP_056958.3	2, 3	279
	NM_203283.2	NP_976028.1	2, 3	216
	NM_203284.2	NP_976029.1	3, 4	462
	XM_005248161.3	XP_005248218.1	3, 4	346
	XM_011513840.2	XP_011512142.1	3, 4	738
	XM_017008170.1	XP_016863659.1	2, 3	135
	XM_017008171.1	XP_016863660.1	2, 3	114
	XM_017008172.1	XP_016863661.1	3, 4	277
	XM_017008173.1	XP_016863662.1	3, 4	555
	XM_017008174.1	XP_016863663.1	3, 4	371
	XM_017008175.1	XP_016863664.1	3, 4	287
GenBank mRNA	AK302230.1	-	2, 3	69
	AK303244.1	-	2, 3	128
	AK311419.1	-	2, 3	115
	BC020780.1	-	2, 3	216	4718839
	BC064976.1	-	3, 4	237	6152924
	BE269143.1	-	3, 4	242
	BM472788.1	-		286
	BM555733.1	-	3, 4	440
	BQ216033.1	-	2, 3	260
	D14041.1	-		112
	DC361185.1	-	2, 3	279
	DC389691.1	-	3, 4	462
	L07872.1	-	2, 3	174
	L07874.1	-	2, 3	291
	L07875.1	-	3, 4	354
	L07876.1	-	2, 3	219
	Z36843.1	-	2, 3	217

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001106631, XM_008770190, XM_008770193, XM_008770191, XM_008770192.

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
angiogenesis
somitogenesis
epithelial to mesenchymal transition
blood vessel remodeling
inflammatory response to antigenic stimulus
secondary heart field specification
outflow tract morphogenesis
endocardium morphogenesis
epithelial to mesenchymal transition involved in endocardial cushion formation
cardiac left ventricle morphogenesis
ventricular trabecula myocardium morphogenesis
regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
DNA recombination
transcription initiation from RNA polymerase II promoter
humoral immune response
Notch signaling pathway
positive regulation of transcription of Notch receptor target
negative regulation of cell proliferation
auditory receptor cell fate commitment
epidermal cell fate specification
pituitary gland development
B cell differentiation
keratinocyte differentiation
negative regulation of ossification
positive regulation of BMP signaling pathway
somatic stem cell population maintenance
dorsal aorta morphogenesis
atrioventricular canal development
defense response to bacterium
myeloid dendritic cell differentiation
negative regulation of cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of timing of cell differentiation
sebaceous gland development
hair follicle maturation
positive regulation of cardiac muscle cell proliferation
Clara cell differentiation
labyrinthine layer blood vessel development
arterial endothelial cell fate commitment
Notch signaling involved in heart development
positive regulation of transcription from RNA polymerase II promoter in response to hypoxia
blood vessel lumenization
interleukin-4 secretion
blood vessel endothelial cell fate specification
positive regulation of ERBB signaling pathway
positive regulation of ephrin receptor signaling pathway
positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
positive regulation of cell proliferation involved in heart morphogenesis

Function(s)

recombinase activity
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II repressing transcription factor binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
sequence-specific DNA binding
protein N-terminus binding