145568

• Gene Symbol: EGR2
• Gene Name: early growth response 2
• Gene Aliases: AT591, CMT1D, CMT4E, KROX20
• Chromosome Location: Chr.10: 62811996 - 62819167 on Build GRCh38
• UniGene ID: Hs.1395
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: EGR2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000399.4	NP_000390.2	2	625
	NM_001136177.2	NP_001129649.1	3	442
	NM_001136178.1	NP_001129650.1	4	483
	NM_001136179.2	NP_001129651.1	3	525
	NM_001321037.1	NP_001307966.1	3	342
	XM_011539427.1	XP_011537729.1	3	328
GenBank mRNA	AF139463.1	-	2	407
	AK091399.1	-	3	460
	AK296830.1	-	3	333
	AK312813.1	-	4	484
	BC035625.1	-	2	600	5208710
	CR749641.1	-	2	602
	DA581108.1	-	3	428
	J04076.1	-	2	327
	KU178040.1	-	2	274

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053633, XM_008772857, AB032420, D83508, U78102, and others.
This siRNA also targets the following transcripts in Mouse: NM_010118, AK153882, BC009093, BY742929, AK155585.

Panther Classification:

Molecular Function -

C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

transcription from RNA polymerase II promoter
protein export from nucleus
brain development
peripheral nervous system development
learning or memory
rhythmic behavior
motor neuron axon guidance
Schwann cell differentiation
protein sumoylation
facial nerve structural organization
rhombomere 3 formation
rhombomere 5 formation
regulation of ossification
response to insulin
brain segmentation
skeletal muscle cell differentiation
myelination
fat cell differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of neuronal synaptic plasticity
cellular response to organic substance

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II activating transcription factor binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
ligase activity
ubiquitin protein ligase binding
transcription regulatory region DNA binding
metal ion binding
HMG box domain binding