146027

Gene Symbol:

AKR1C4 AKR1C2

Gene Name:

aldo-keto reductase family 1, member C4

aldo-keto reductase family 1, member C2

Gene Aliases:

3-alpha-HSD, C11, CDR, CHDR, DD-4, DD4, HAKRA

AKR1C-pseudo, BABP, DD, DD-2, DD/BABP, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8, TDD

Chromosome Location:

Chr.10: 5196835 - 5218947 on Build GRCh38

Chromosome Location:

Chr.10: 4987775 - 5018033 on Build GRCh38

UniGene ID:

Hs.567245

Hs.460260

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: AKR1C4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001818.3	NP_001809.3	9	1020
GenBank mRNA	BC020744.1	-	9	1020	4734943
	D26125.1	-	9	983
	M33375.1	-	9	985
	S68287.1	-	9	994

Gene Symbol: AKR1C2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	M33376.1	-	9	942

More Information

Panther Classification:

Molecular Function -

oxidoreductase, reductase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

retinoid metabolic process
bile acid biosynthetic process
steroid metabolic process
androgen metabolic process
bile acid and bile salt transport
daunorubicin metabolic process
doxorubicin metabolic process
oxidation-reduction process
cellular response to jasmonic acid stimulus

Function(s)

retinal dehydrogenase activity
aldo-keto reductase (NADP) activity
electron carrier activity
bile acid transmembrane transporter activity
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
androsterone dehydrogenase activity
chlordecone reductase activity