146246

• Gene Symbol: ERBB3
• Gene Name: erb-b2 receptor tyrosine kinase 3
• Gene Aliases: ErbB-3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3
• Chromosome Location: Chr.12: 56080025 - 56103507 on Build GRCh38
• UniGene ID: Hs.118681
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ERBB3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001005915.1	NP_001005915.1	2	387
	NM_001982.3	NP_001973.2	2	470
GenBank mRNA	AK291681.1	-	2	323
	AK294719.1	-	2	327
	AK295650.1	-	3	237
	BC002706.2	-	2	290
	BC082992.1	-	2	309	6147464
	BM837872.1	-	2	386
	BT007226.1	-	2	194
	DC344156.1	-	2	470
	DC347955.1	-	2	408
	M29366.1	-	2	293
	M34309.1	-	2	392
	S61953.1	-	2	293

More Information

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
endocardial cushion development
negative regulation of cell adhesion
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
peripheral nervous system development
heart development
negative regulation of signal transduction
Schwann cell differentiation
phosphatidylinositol 3-kinase signaling
regulation of phosphatidylinositol 3-kinase signaling
positive regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
cranial nerve development
ERBB2 signaling pathway
wound healing
regulation of cell proliferation
negative regulation of neuron apoptotic process
positive regulation of GTPase activity
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
negative regulation of secretion
neuron apoptotic process
positive regulation of protein tyrosine kinase activity
positive regulation of calcineurin-NFAT signaling cascade
extrinsic apoptotic signaling pathway in absence of ligand
regulation of cell motility

Function(s)

protein tyrosine kinase activity
transmembrane signaling receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
ATP binding
growth factor binding
protein tyrosine kinase activator activity
neuregulin binding
identical protein binding
protein homodimerization activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
protein heterodimerization activity