146272

• Gene Symbol: FGF2
• Gene Name: fibroblast growth factor 2
• Gene Aliases: BFGF, FGF-2, FGFB, HBGF-2
• Chromosome Location: Chr.4: 122826708 - 122898235 on Build GRCh38
• UniGene ID: Hs.284244
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: FGF2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002006.4	NP_001997.5	1, 2	646
GenBank mRNA	AB451321.1	-	1, 2	179
	AB451450.1	-	1, 2	179
	AY820133.1	-	1, 2	152
	BC111737.1	-	2, 3	53
	J04513.1	-	1, 2	645
	M17599.1	-	1, 2	185
	M27968.1	-	1, 2	518
	S47380.1	-	1, 2	64

More Information

Panther Classification:

Molecular Function -

growth factor, intercellular signal molecule

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPK activity
branching involved in ureteric bud morphogenesis
positive regulation of endothelial cell proliferation
cell migration involved in sprouting angiogenesis
phosphatidylinositol biosynthetic process
chemotaxis
signal transduction
Ras protein signal transduction
nervous system development
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
organ morphogenesis
negative regulation of fibroblast migration
positive regulation of phospholipase C activity
regulation of phosphatidylinositol 3-kinase signaling
growth factor dependent regulation of skeletal muscle satellite cell proliferation
peptidyl-tyrosine phosphorylation
extracellular matrix organization
hyaluronan catabolic process
inositol phosphate biosynthetic process
somatic stem cell population maintenance
phosphatidylinositol-3-phosphate biosynthetic process
wound healing
positive regulation of cell fate specification
positive regulation of MAP kinase activity
positive regulation of blood vessel endothelial cell migration
negative regulation of blood vessel endothelial cell migration
positive regulation of GTPase activity
positive regulation of phosphatidylinositol 3-kinase activity
regulation of angiogenesis
positive regulation of angiogenesis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
embryonic morphogenesis
positive chemotaxis
release of sequestered calcium ion into cytosol
positive regulation of cell division
positive regulation of cardiac muscle cell proliferation
negative regulation of cell death
chondroblast differentiation
negative regulation of wound healing
positive regulation of ERK1 and ERK2 cascade
positive regulation of sprouting angiogenesis
regulation of endothelial cell chemotaxis to fibroblast growth factor
positive regulation of endothelial cell chemotaxis to fibroblast growth factor

Function(s)

protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
fibroblast growth factor receptor binding
cytokine activity
protein binding
growth factor activity
heparin binding
1-phosphatidylinositol-3-kinase activity
ligand-dependent nuclear receptor transcription coactivator activity
chemoattractant activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity