146463

• Gene Symbol: DVL2
• Gene Name: dishevelled segment polarity protein 2
• Gene Aliases: -
• Chromosome Location: Chr.17: 7225342 - 7234548 on Build GRCh38
• UniGene ID: Hs.118640
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DVL2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_004422.2	NP_004413.1	12	1633
	XM_005256502.1	XP_005256559.1	12	1625
	XM_017024298.1	XP_016879787.1	9	979
GenBank mRNA	AF006012.1	-	12	1357
	AK026019.1	-	11	1159
	AK297099.1	-	12	1389
	AK304229.1	-	12	1343
	AK312829.1	-	12	1634
	BC014844.1	-	12	1446	3852554
	BT009822.1	-	12	1351

More Information

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

neural tube closure
positive regulation of protein phosphorylation
outflow tract morphogenesis
transcription from RNA polymerase II promoter
segment specification
heart development
Wnt signaling pathway
convergent extension involved in neural plate elongation
cellular protein localization
hippo signaling
non-canonical Wnt signaling pathway
positive regulation of JUN kinase activity
positive regulation of GTPase activity
canonical Wnt signaling pathway involved in regulation of cell proliferation
positive regulation of transcription, DNA-templated
positive regulation of sequence-specific DNA binding transcription factor activity
protein oligomerization
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
positive regulation of protein tyrosine kinase activity
negative regulation of canonical Wnt signaling pathway
cochlea morphogenesis
planar cell polarity pathway involved in neural tube closure
positive regulation of canonical Wnt signaling pathway
beta-catenin destruction complex disassembly

Function(s)

frizzled binding
protein binding
protein kinase binding
protein domain specific binding
protein binding, bridging
identical protein binding
protein self-association
Rac GTPase binding