146563

• Gene Symbol: DOCK2
• Gene Name: dedicator of cytokinesis 2
• Gene Aliases: IMD40
• Chromosome Location: Chr.5: 169637247 - 170083382 on Build GRCh38
• UniGene ID: Hs.586174
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DOCK2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_004946.2	NP_004937.1	8, 9	835
	XM_005265830.3	XP_005265887.1	8, 9	835
	XM_011534448.2	XP_011532750.1	8, 9	835
	XM_011534449.2	XP_011532751.1	8, 9	835
	XM_011534450.2	XP_011532752.1	8, 9	835
	XM_011534451.2	XP_011532753.1	8, 9	835
	XM_017009189.1	XP_016864678.1	8, 9	835
	XM_017009190.1	XP_016864679.1	8, 9	835
GenBank mRNA	BC104900.1	-	8, 9	791	8143903
	BC113457.1	-	8, 9	791	8322509
	BC143358.1	-	8, 9	791
	D86964.1	-	8, 9	793

More Information

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

membrane raft polarization
establishment of T cell polarity
immunological synapse formation
myeloid dendritic cell activation involved in immune response
chemotaxis
small GTPase mediated signal transduction
actin cytoskeleton organization
positive regulation of GTPase activity
macropinocytosis
positive thymic T cell selection
negative thymic T cell selection
alpha-beta T cell proliferation
regulation of defense response to virus by virus
positive regulation of phagocytosis

Function(s)

GTPase activator activity
protein binding
Rac guanyl-nucleotide exchange factor activity
T cell receptor binding