1468

• Gene Symbol: FGR
• Gene Name: FGR proto-oncogene, Src family tyrosine kinase
• Gene Aliases: SRC2, c-fgr, c-src2, p55-Fgr, p55c-fgr, p58-Fgr, p58c-fgr
• Chromosome Location: Chr.1: 27612289 - 27635561 on Build GRCh38
• UniGene ID: Hs.1422
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: FGR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001042729.1	NP_001036194.1	4	520
	NM_001042747.1	NP_001036212.1	4	579
	NM_005248.2	NP_005239.1	4	536
	XM_006710452.2	XP_006710515.1	5	587
	XM_011541010.1	XP_011539312.1	4	501
	XM_011541012.1	XP_011539314.1	4	536
	XM_011541013.2	XP_011539315.1	4	536
GenBank mRNA	AK130188.1	-	4	498
	AK301078.1	-	4	492
	BC064382.1	-	4	449	5734966
	DA139476.1	-	4	536
	DA952771.1	-	4	475
	DA960178.1	-	4	503
	M19722.1	-	2	455
	M27454.1	-	4	461

More Information

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

immune response-regulating cell surface receptor signaling pathway
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
integrin-mediated signaling pathway
regulation of cell shape
response to virus
positive regulation of phosphatidylinositol 3-kinase signaling
cell migration
peptidyl-tyrosine phosphorylation
cell differentiation
positive regulation of cell migration
peptidyl-tyrosine autophosphorylation
Fc-gamma receptor signaling pathway involved in phagocytosis
regulation of cell proliferation
positive regulation of mast cell degranulation
positive regulation of phosphatidylinositol 3-kinase activity
innate immune response
regulation of innate immune response
regulation of protein kinase activity
protein autophosphorylation
positive regulation of cytokine secretion
regulation of phagocytosis
defense response to Gram-positive bacterium

Function(s)

phosphotyrosine binding
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein binding
ATP binding
protein kinase binding
immunoglobulin receptor binding
Fc-gamma receptor I complex binding