147147

• Gene Symbol: GRK2
• Gene Name: G protein-coupled receptor kinase 2
• Gene Aliases: ADRBK1, BARK1, BETA-ARK1
• Chromosome Location: Chr.11: 67266420 - 67286558 on Build GRCh38
• UniGene ID: Hs.83636
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: GRK2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001619.3	NP_001610.2	6, 7	777
	XM_011544773.1	XP_011543075.1	6, 7	518
GenBank mRNA	AB209588.1	-	5, 6	1133
	BC037963.1	-	6, 7	756	5585846
	BC090863.1	-	6, 7	745	6203199
	KU177896.1	-	6, 7	511
	KU177897.1	-	6, 7	511
	M80776.1	-	6, 7	526
	X61157.1	-	6, 7	618

More Information

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

desensitization of G-protein coupled receptor protein signaling pathway
negative regulation of the force of heart contraction by chemical signal
G-protein coupled acetylcholine receptor signaling pathway
tachykinin receptor signaling pathway
heart development
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
viral genome replication
receptor internalization
positive regulation of catecholamine secretion
negative regulation of striated muscle contraction
viral entry into host cell
cardiac muscle contraction

Function(s)

protein kinase activity
G-protein coupled receptor kinase activity
protein binding
ATP binding
alpha-2A adrenergic receptor binding
Edg-2 lysophosphatidic acid receptor binding
beta-adrenergic receptor kinase activity