148621

• Gene Symbol: EXOSC3
• Gene Name: exosome component 3
• Gene Aliases: CGI-102, PCH1B, RRP40, Rrp40p, bA3J10.7, hRrp-40, p10
• Chromosome Location: Chr.9: 37779714 - 37785092 on Build GRCh38
• UniGene ID: Hs.602571
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: EXOSC3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001002269.2	NP_001002269.1	3	753
	NM_016042.3	NP_057126.2	4	905
GenBank mRNA	AF151860.1	-	4	831
	AF229833.1	-	3	450
	AF281132.1	-	4	881
	AK289571.1	-	3	722
	AK290864.1	-	4	870
	BC002437.2	-	4	869	3346075
	BC008880.2	-	4	859	4300826

More Information

Panther Classification:

Molecular Function -

RNA processing factor

Gene Ontology Categories:

Process(es)

exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
rRNA processing
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
U4 snRNA 3'-end processing
regulation of mRNA stability
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
DNA deamination
isotype switching
positive regulation of isotype switching
CUT catabolic process
nuclear polyadenylation-dependent rRNA catabolic process
nuclear polyadenylation-dependent tRNA catabolic process
nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription
polyadenylation-dependent snoRNA 3'-end processing

Function(s)

3'-5'-exoribonuclease activity
RNA binding
exoribonuclease activity
protein binding