149429

• Gene Symbol: E2F7
• Gene Name: E2F transcription factor 7
• Gene Aliases: -
• Chromosome Location: Chr.12: 77021246 - 77065580 on Build GRCh38
• UniGene ID: Hs.416375
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: E2F7
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_203394.2	NP_976328.2	5	792
	XM_011537966.2	XP_011536268.1	5	792
	XM_011537969.2	XP_011536271.1	4	355
GenBank mRNA	AK097677.1	-	3	385
	BC136366.1	-	5	631	9020353
	BC136367.1	-	5	631	9020354

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001108092, XM_006241320, XM_006241321.
This siRNA also targets the following transcripts in Mouse: NM_178609, AK143686, BC150772, AK041481, BC145429, and others.

Panther Classification:

Molecular Function -

RNA metabolism protein, nucleic acid metabolism protein, general transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
placenta development
sprouting angiogenesis
transcription, DNA-templated
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
negative regulation of cell proliferation
DNA damage response, signal transduction by p53 class mediator
negative regulation of cytokinesis
positive regulation of DNA endoreduplication
positive regulation of transcription from RNA polymerase II promoter
trophoblast giant cell differentiation
chorionic trophoblast cell differentiation
hepatocyte differentiation
negative regulation of transcription involved in G1/S transition of mitotic cell cycle
negative regulation of G1/S transition of mitotic cell cycle

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
core promoter binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
identical protein binding