150296

• Gene Symbol: Prox1
• Gene Name: prospero homeobox 1
• Gene Aliases: A230003G05Rik
• Chromosome Location: Chr.1: 190118035 - 190170825 on Build GRCm38
• UniGene ID: Mm.132579
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Prox1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008937.2	NP_032963.1	2	576
GenBank mRNA	AF061576.1	-	1	163
	AK052889.1	-	2	610
	AK143179.1	-	2	400
	BC051411.1	-	2	576	6490801

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_002763, NM_001270616, DA743374, U44060, BC024201.
This siRNA also targets the following transcripts in Rat: NM_001107201, XM_006250456, XM_006250454, XM_006250455, XM_006250458.

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
cell fate determination
positive regulation of endothelial cell proliferation
lymph vessel development
lymphangiogenesis
lens morphogenesis in camera-type eye
hepatocyte cell migration
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
positive regulation of cell proliferation
negative regulation of cell proliferation
regulation of gene expression
positive regulation of endothelial cell migration
dentate gyrus development
cerebellar granule cell differentiation
skeletal muscle thin filament assembly
regulation of circadian rhythm
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of viral genome replication
endothelial cell differentiation
positive regulation of cyclin-dependent protein serine/threonine kinase activity
positive regulation of cell cycle
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
rhythmic process
inner ear development
venous blood vessel morphogenesis
ventricular cardiac myofibril assembly
atrial cardiac muscle tissue morphogenesis
ventricular cardiac muscle tissue morphogenesis
endocardium formation
positive regulation of sarcomere organization
ventricular septum morphogenesis
aorta smooth muscle tissue morphogenesis
positive regulation of heart growth
lymphatic endothelial cell differentiation
regulation of transcription involved in lymphatic endothelial cell fate commitment
branching involved in pancreas morphogenesis
lens fiber cell morphogenesis
negative regulation of bile acid biosynthetic process
hepatocyte proliferation
acinar cell differentiation
neuronal stem cell population maintenance
positive regulation of cell cycle checkpoint
positive regulation of neural precursor cell proliferation
positive regulation of forebrain neuron differentiation

Function(s)

RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription corepressor activity
protein binding
ligand-dependent nuclear receptor binding
sequence-specific DNA binding
transcription regulatory region DNA binding
DBD domain binding
LBD domain binding