15039

• Gene Symbol: HERC2
• Gene Name: HECT and RLD domain containing E3 ubiquitin protein ligase 2
• Gene Aliases: D15F37S1, MRT38, SHEP1, jdf2, p528
• Chromosome Location: Chr.15: 28111037 - 28322173 on Build GRCh38
• UniGene ID: Hs.434890
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: HERC2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_004667.5	NP_004658.3	5	597
	XM_005268276.4	XP_005268333.1	4	727
	XM_006720726.3	XP_006720789.1	5	618
	XM_006720727.3	XP_006720790.1	5	618
	XM_011522131.2	XP_011520433.1	3	383
	XM_017022695.1	XP_016878184.1	4	544
	XM_017022696.1	XP_016878185.1	4	487
GenBank mRNA	AF071172.3	-	5	549
	BC045544.1	-	6	707

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001107520, XM_006229301, XM_006229304, XM_006229300, XM_006229302.
This siRNA also targets the following transcripts in Mouse: NM_010418, AF061529, AK165121, AF071173.

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

double-strand break repair via nonhomologous end joining
intracellular protein transport
cellular response to DNA damage stimulus
spermatogenesis
protein ubiquitination
protein sumoylation
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
positive regulation of GTPase activity

Function(s)

ubiquitin-protein transferase activity
guanyl-nucleotide exchange factor activity
protein binding
zinc ion binding
ligase activity
ubiquitin protein ligase binding
SUMO binding