150587

• Gene Symbol: Rock1
• Gene Name: Rho-associated coiled-coil containing protein kinase 1
• Gene Aliases: 1110055K06Rik, Rock-I
• Chromosome Location: Chr.18: 10064401 - 10181792 on Build GRCm38
• UniGene ID: Mm.6710
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Rock1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_009071.2	NP_033097.1	4, 5	897
GenBank mRNA	AK149793.1	-	4, 5	1152
	BC057154.1	-	4, 5	897
	BC066873.1	-	4, 5	574
	U58512.1	-	4, 5	422

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_005406, BC113114, AK307388, U43195, AK057038.
This siRNA also targets the following transcripts in Rat: NM_031098, XM_008771957, XM_006254400, XM_006254401, U61266, and others.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

apical constriction
protein phosphorylation
apoptotic process
cytoskeleton organization
leukocyte cell-cell adhesion
signal transduction
Rho protein signal transduction
phosphorylation
negative regulation of angiogenesis
membrane to membrane docking
actin cytoskeleton organization
bleb assembly
negative regulation of protein binding
regulation of actin filament-based process
intracellular signal transduction
negative regulation of neuron apoptotic process
regulation of keratinocyte differentiation
leukocyte migration
leukocyte tethering or rolling
myoblast migration
regulation of stress fiber assembly
regulation of cytoskeleton organization
positive regulation of focal adhesion assembly
regulation of establishment of cell polarity

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
Rho GTPase binding
GTP-Rho binding
metal ion binding