151218

• Gene Symbol: Pparg
• Gene Name: peroxisome proliferator activated receptor gamma
• Gene Aliases: Nr1c3, PPAR-gamma, PPAR-gamma2, PPARgamma, PPARgamma2
• Chromosome Location: Chr.6: 115360879 - 115490404 on Build GRCm38
• UniGene ID: Mm.3020
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pparg
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011146.3	NP_035276.2	4	550
GenBank mRNA	AB644275.1	-	5	556
	AY208184.1	-	4	550
	AY243585.1	-	4	550
	BC021798.1	-	4	550	4191539
	CN701591.1	-	5	560
	CT010340.1	-	4	505
	EF062476.1	-	4	541
	GQ868647.1	-	3	308
	GQ868648.1	-	3	288
	GQ868649.1	-	3	308
	GQ868650.1	-	3	288
	U01664.1	-	5	582
	U01841.1	-	5	905
	U09138.1	-	4	544
	U10374.1	-	3	415

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001145366, NM_001145367, NM_013124, XM_006237009, AF156666, and others.

Panther Classification:

Molecular Function -

C4 zinc finger nuclear receptor, DNA-binding transcription factor, zinc finger transcription factor, gene-specific transcriptional regulator

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
negative regulation of cytokine production
placenta development
response to dietary excess
diet induced thermogenesis
negative regulation of acute inflammatory response
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
signal transduction
regulation of blood pressure
negative regulation of cell proliferation
response to light stimulus
regulation of gene expression
negative regulation of macrophage derived foam cell differentiation
negative regulation of receptor biosynthetic process
negative regulation of cholesterol storage
negative regulation of sequestering of triglyceride
long-chain fatty acid transport
regulation of lipid metabolic process
fatty acid oxidation
monocyte differentiation
negative regulation of cell growth
intracellular receptor signaling pathway
epithelial cell differentiation
response to food
response to retinoic acid
cellular response to insulin stimulus
negative regulation of collagen biosynthetic process
response to lipid
peroxisome proliferator activated receptor signaling pathway
glucose homeostasis
regulation of circadian rhythm
lipoprotein transport
positive regulation of apoptotic process
steroid hormone mediated signaling pathway
cell fate commitment
fat cell differentiation
regulation of fat cell differentiation
positive regulation of fat cell differentiation
low-density lipoprotein particle receptor biosynthetic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of fatty acid oxidation
cell maturation
rhythmic process
negative regulation of smooth muscle cell proliferation
positive regulation of oligodendrocyte differentiation
white fat cell differentiation
brown fat cell differentiation
positive regulation of sequence-specific DNA binding transcription factor activity
negative regulation of telomerase activity
response to low-density lipoprotein particle
positive regulation of phagocytosis, engulfment
negative regulation of interferon-gamma-mediated signaling pathway
regulation of transcription involved in cell fate commitment
cellular response to lithium ion
cellular response to organic cyclic compound
negative regulation of peptide hormone secretion
negative regulation of cellular response to insulin stimulus
negative regulation of pancreatic stellate cell proliferation

Function(s)

RNA polymerase II regulatory region DNA binding
core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
transcription factor binding
drug binding
zinc ion binding
enzyme binding
protein phosphatase binding
estrogen receptor binding
ligand-dependent nuclear receptor transcription coactivator activity
activating transcription factor binding
sequence-specific DNA binding
transcription regulatory region DNA binding
metal ion binding
retinoid X receptor binding
arachidonic acid binding
WW domain binding
alpha-actinin binding