151324

• Gene Symbol: Ptgs2
• Gene Name: prostaglandin-endoperoxide synthase 2
• Gene Aliases: COX2, Cox-2, PGHS-2, PHS-2, Pghs2, TIS10
• Chromosome Location: Chr.1: 150100124 - 150108017 on Build GRCm38
• UniGene ID: Mm.292547
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ptgs2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011198.3	NP_035328.2	10	1884
GenBank mRNA	AK049923.1	-	10	1875
	AK144726.1	-	10	1909
	AK144956.1	-	10	1907
	AK149820.1	-	10	1907
	AK166221.1	-	10	1907
	AK172161.1	-	10	1909
	BC052900.1	-	10	1751	30059181
	M64291.1	-	10	1908
	M88242.1	-	10	1884
	M94967.1	-	10	1909

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_017232, U04300, AF233596, S67722, L20085, and others.

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

prostaglandin biosynthetic process
angiogenesis
lipid metabolic process
fatty acid metabolic process
fatty acid biosynthetic process
prostaglandin metabolic process
inflammatory response
response to oxidative stress
embryo implantation
learning
memory
regulation of blood pressure
positive regulation of cell proliferation
negative regulation of cell proliferation
positive regulation of vascular endothelial growth factor production
positive regulation of cell death
sensory perception of pain
cyclooxygenase pathway
keratinocyte differentiation
bone mineralization
ovulation
positive regulation of fever generation
positive regulation of synaptic plasticity
negative regulation of synaptic transmission, dopaminergic
response to lipopolysaccharide
response to cytokine
maintenance of blood-brain barrier
regulation of cell proliferation
positive regulation of NF-kappaB import into nucleus
anagen
positive regulation of apoptotic process
positive regulation of nitric oxide biosynthetic process
negative regulation of cell cycle
positive regulation of vasoconstriction
negative regulation of smooth muscle contraction
positive regulation of smooth muscle contraction
decidualization
positive regulation of smooth muscle cell proliferation
brown fat cell differentiation
negative regulation of calcium ion transport
positive regulation of synaptic transmission, glutamatergic
oxidation-reduction process
cellular response to fluid shear stress
positive regulation of transforming growth factor beta production
positive regulation of cell migration involved in sprouting angiogenesis
positive regulation of fibroblast growth factor production
positive regulation of brown fat cell differentiation
positive regulation of platelet-derived growth factor production

Function(s)

peroxidase activity
prostaglandin-endoperoxide synthase activity
lipid binding
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
enzyme binding
heme binding
protein homodimerization activity
metal ion binding
dioxygenase activity