151415

• Gene Symbol: Rasgrp1
• Gene Name: RAS guanyl releasing protein 1
• Gene Aliases: Rasgrp
• Chromosome Location: Chr.2: 117279993 - 117342877 on Build GRCm38
• UniGene ID: Mm.42150
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Rasgrp1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011246.2	NP_035376.1	11	1579
GenBank mRNA	AF106070.1	-	11	1423
	AK047613.1	-	6	881
	AK134005.1	-	11	1592
	AK141524.1	-	11	1704
	BC057120.1	-	11	1579	6831137
	BC057341.1	-	11	1579	6831137

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_019211, AF081196, AF060819.

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

cytokine production
positive regulation of protein phosphorylation
inflammatory response to antigenic stimulus
small GTPase mediated signal transduction
Ras protein signal transduction
regulation of phosphatidylinositol 3-kinase signaling
cell differentiation
secretory granule localization
positive regulation of granulocyte macrophage colony-stimulating factor production
positive regulation of tumor necrosis factor production
intracellular signal transduction
regulation of GTPase activity
mast cell degranulation
positive regulation of MAP kinase activity
positive regulation of GTPase activity
positive regulation of natural killer cell mediated cytotoxicity
positive regulation of JNK cascade
positive regulation of Ras protein signal transduction
vesicle transport along microtubule
protein oligomerization
regulation of ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
activation of GTPase activity
positive regulation of interferon-gamma secretion

Function(s)

phosphatidylserine binding
guanyl-nucleotide exchange factor activity
Ras guanyl-nucleotide exchange factor activity
calcium ion binding
zinc ion binding
diacylglycerol binding
phosphatidylcholine binding
protein homodimerization activity
metal ion binding