151451

• Gene Symbol: Rest
• Gene Name: RE1-silencing transcription factor
• Gene Aliases: 2610008J04Rik, AA407358, NRSF, REST4
• Chromosome Location: Chr.5: 77265494 - 77286432 on Build GRCm38
• UniGene ID: Mm.28840
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Rest
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011263.2	NP_035393.2	4	1365
GenBank mRNA	AB024496.1	-	3	1061
	AB221589.1	-	3	1060
	AK004945.2	-	4	1368
	AK156514.1	-	4	1351
	BC096434.1	-	4	1288
	BC127065.1	-	3	1061	40110015
	U13878.1	-	3	836

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031788, XM_006250848, XM_006250847, XM_006250849, AF037199.

Panther Classification:

Molecular Function -

C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
hematopoietic progenitor cell differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
negative regulation of cell proliferation
negative regulation of gene expression
negative regulation of aldosterone biosynthetic process
regulation of ion transmembrane transport
cellular response to drug
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation by host of viral transcription
negative regulation of neuron differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of calcium ion-dependent exocytosis
negative regulation of insulin secretion
negative regulation of neurogenesis
cardiac muscle cell myoblast differentiation
histone H4 deacetylation
cellular response to electrical stimulus
cellular response to glucocorticoid stimulus
potassium ion transmembrane transport
negative regulation of cortisol biosynthetic process
negative regulation of dense core granule biogenesis
negative regulation of mesenchymal stem cell differentiation
negative regulation of amniotic stem cell differentiation

Function(s)

RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter sequence-specific DNA binding
core promoter binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
nucleic acid binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
outward rectifier potassium channel activity
protein complex binding
transcription regulatory region DNA binding
metal ion binding