151656

• Gene Symbol: Shc1
• Gene Name: src homology 2 domain-containing transforming protein C1
• Gene Aliases: Shc, ShcA, p66, p66shc
• Chromosome Location: Chr.3: 89418481 - 89430029 on Build GRCm38
• UniGene ID: Mm.86595
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Shc1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001113331.2	NP_001106802.1	1	654
	NM_011368.5	NP_035498.2	2	256
GenBank mRNA	AK036980.1	-	1	1643
	AK049357.1	-	2	229
	AK155158.1	-	1	649
	AK203451.1	-	1	77
	AK211173.1	-	1	74
	BC036172.1	-	2	207	4988907
	U15784.1	-	2	146

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_003029, NM_001130040, NM_001202859, NM_183001, NM_001130041, and others.
This siRNA also targets the following transcripts in Rat: NM_053517, NM_001164060, BC088298.

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPK activity
angiogenesis
signal transduction
epidermal growth factor receptor signaling pathway
heart development
aging
insulin receptor signaling pathway
single organismal cell-cell adhesion
actin cytoskeleton organization
neuron differentiation
neuron projection development
actin cytoskeleton reorganization
intracellular signal transduction
regulation of growth
regulation of cell proliferation
positive regulation of DNA replication
positive regulation of vasoconstriction
positive regulation of smooth muscle cell proliferation

Function(s)

phosphotyrosine binding
epidermal growth factor receptor binding
insulin receptor binding
insulin-like growth factor receptor binding
neurotrophin TRKA receptor binding
protein binding
protein kinase binding
receptor tyrosine kinase binding
protein complex binding
ephrin receptor binding
phosphoprotein binding
protein phosphatase 2A binding